Vitamin D Is Inversely Related to Obesity: Cross-Sectional Study in a Small Cohort of Serbian Adults
Autor: | Milica Zekovic, Sanja Stankovic, Maria Glibetic, Radmila Obrenovic, Manja Zec, Ana Pantovic |
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Rok vydání: | 2019 |
Předmět: |
Adult
Male 0301 basic medicine obesity Cross-sectional study Nutritional Status Medicine (miscellaneous) 030209 endocrinology & metabolism Bone health Mineralization (biology) Cohort Studies 03 medical and health sciences 0302 clinical medicine Environmental health gender Vitamin D and neurology cross-sectional study Humans Medicine Obesity Vitamin D 030109 nutrition & dietetics Nutrition and Dietetics Waist-Hip Ratio business.industry Middle Aged Overweight Vitamin D Deficiency medicine.disease Diet 3. Good health Cross-Sectional Studies Cohort cardiometabolic Regression Analysis Female Waist Circumference business Serbia |
Zdroj: | Journal of the American College of Nutrition |
ISSN: | 1541-1087 0731-5724 |
DOI: | 10.1080/07315724.2018.1538828 |
Popis: | Objective: Vitamin D (vitD) mediates numerous health conditions other than bone health and mineralization. Its role in cardiometabolic condition is still inconclusive. Methods: We conducted a cross-sectional study in 87 apparently healthy Serbian adults. We assessed their dietary intake, anthropometric and biochemical parameters, blood pressure, and vitD status (as serum 25-hydroxyvitamin D, 25(OH)D). Unexpectedly, the status was significantly higher in January than in July. Therefore, we pooled the data from two time points, to enhance the statistical power for carrying out association analyses. We employed linear regression models to evaluate the associations between vitD status and the obesity biomarkers of serum lipids and blood pressure. Results: Mean vitD intake of 3.85 +/- 4.71 mu g in the cohort was below recommended. Of the subjects in the pooled cohort, 60.58% were vitD deficient (with serum 25(OH)D below 50 nmol/L), with the majority of them being women who were overweight. VitD status tended to be inversely related to percent body fat and waist/height ratio in the crude regression model. After age and gender adjustment, the status was significantly related to waist circumference, waist/height ratio, and waist/hip ratio (beta = -0.116, 95% confidence interval [CI]: -0.206, -0.025, beta = -0.001, 95% CI: -0.001, 0.000, and beta = -0.001, 95% CI: -0.001, 0.000, respectively). These associations remained only within women. Fully adjusted models supported the notion of vitD being independently associated with central adiposity, regardless of age, gender, and total obesity. Conclusions: In apparently healthy adults with low vitD intake, vitD status was inversely associated with obesity parameters, pronouncedly in women. Our data support the need for development and implementation of public health policies on increasing vitD intake also as part of obesity management strategies. |
Databáze: | OpenAIRE |
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