Disinfectants used in stomatology and SARS-CoV-2 infection
| Autor: | Agata Kryczyk-Poprawa, Magdalena Stawarz-Janeczek, Bożena Muszyńska, Jolanta Pytko-Polończyk, Włodzimierz Opoka |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
SARS-CoV-2
business.industry Disinfectant Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Chlorhexidine COVID-19 Review Article stomatology 030206 dentistry Sterilization (microbiology) Asepsis Microbiology 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine chemistry Peracetic acid medicine Infection control Antimicrobial action 030212 general & internal medicine dental practice business General Dentistry medicine.drug |
| Zdroj: | European Journal of Dentistry |
| Popis: | Effective disinfection is a basic procedure in medical facilities, including those conducting dental surgeries, where treatments for tissue discontinuity are also performed, as it is an important element of infection prevention. Disinfectants used in dentistry and dental and maxillofacial surgery include both inorganic (hydrogen peroxide, sodium chlorite-hypochlorite) and organic compounds (ethanol, isopropanol, peracetic acid, chlorhexidine, eugenol). Various mechanisms of action of disinfectants have been reported, which include destruction of the structure of bacterial and fungal cell membranes; damage of nucleic acids; denaturation of proteins, which in turn causes inhibition of enzyme activity; loss of cell membrane integrity; and decomposition of cell components. This article discusses the most important examples of substances used as disinfectants in dentistry and presents the mechanisms of their action with particular focus on severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The search was conducted in ScienceDirect, PubMed, and Scopus databases. The interest of scientists in the use of disinfectants in dental practice is constantly growing, which results in the increasing number of publications on disinfection, sterilization, and asepsis. Many disinfectants often possess several of the abovementioned mechanisms of action. In addition, disinfectant preparations used in dental practice either contain one compound or are frequently a mixture of active compounds, which increases their range and effectiveness of antimicrobial action. Currently available information on disinfectants that can be used to prevent SARS-CoV-2 infection in dental practices was summarized. |
| Databáze: | OpenAIRE |
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