Pediatric reference values for serum magnesium levels in Iranian subjects
| Autor: | Asghar Ghasemi, Saleh Zahediasl, Fereidoun Azizi, Leila Syedmoradi |
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| Rok vydání: | 2010 |
| Předmět: |
Male
Pediatrics medicine.medical_specialty Renal Tubular Transport Inborn Errors Adolescent Clinical Biochemistry Hypercalciuria Physiology chemistry.chemical_element Guidelines as Topic Iran Young Adult Insulin resistance Metabolic Diseases Reference Values medicine Humans Magnesium Child business.industry Healthy population Spectrophotometry Atomic Magnesium blood General Medicine medicine.disease Reference intervals Nephrocalcinosis chemistry Reference values Chemistry Clinical Child Preschool Renal tubular transport Female Hypermagnesemia business |
| Zdroj: | Scandinavian journal of clinical and laboratory investigation. 70(6) |
| ISSN: | 1502-7686 |
| Popis: | Magnesium (Mg), an essential element, plays important roles in many physiological functions. Mg deficiency is associated with insulin resistance, cardiovascular disease, and disorders of the nervous system. The aim of this study was to determine reference values for serum Mg concentration in pediatrics. Serum Mg level was measured by flame atomic absorption spectrophotometry in 306 subjects (141 boys and 165 girls), aged 3-19 years, selected from among participants of the Tehran Lipid and Glucose Study. The International Federation of Clinical Chemistry guidelines (IFCC) and the robust method were used for determining reference values for sample sizes greater or less than 120 subjects respectively. The 95% reference values for serum Mg concentrations were 0.76-1.0, 0.75-1.0, and 0.76-0.99 mmol/L in boys, girls, and the all subjects respectively. According to the reference values obtained in this study, the prevalences of hypo- and hypermagnesemia, were 5.9% and 5.6% respectively. In conclusion, the current study presents pediatric reference values for serum Mg levels derived from a randomly selected healthy population, values which could be instrumental in detecting serum Mg abnormalities. |
| Databáze: | OpenAIRE |
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