Facilitated avoidance learning and stress-induced corticosterone levels as a function of age in rats

Autor: Ronald M. Paolino, Tom S. Miya, Ronald E. Johnston
Rok vydání: 1974
Předmět:
Zdroj: Physiologybehavior. 12(2)
ISSN: 0031-9384
Popis: Three month and 6 month old rats were trained in a two-way shuttle box active avoidance task. The procedure consisted of giving each rat 60 acquisition trials which were immediately followed by 60 extinction trials. The older animals acquired the conditioned avoidance response (CAR) faster and required a longer time to extinguish, than the younger animals. The enhanced CAR performance of the older animals could not be attributed to an altered pain threshold but was correlated with a significantly higher plasma corticosterone response to ether-stress. The data are interpreted as being consistent with the notion of a positive relationship between pituarity-adrenal activity and facilitated avoidance learning.
Databáze: OpenAIRE