Use of neuroimaging to understand abnormal pain sensitivity in fibromyalgia
| Autor: | Nancy L. McKendree-Smith, Laurence A. Bradley, Kristin R. Alberts, James M. Mountz, Graciela S. Alarcón, Georg Deutsch |
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| Rok vydání: | 2000 |
| Předmět: |
musculoskeletal diseases
Diagnostic Imaging Male Pain Threshold medicine.medical_specialty Fibromyalgia Central nervous system Pain Sensitivity and Specificity Severity of Illness Index Pain processing Rheumatology Neuroimaging Internal medicine Threshold of pain Severity of illness Medicine Humans Pain Measurement business.industry Brain medicine.disease Magnetic Resonance Imaging nervous system diseases medicine.anatomical_structure Cerebral blood flow Cerebrovascular Circulation Physical therapy Female business Blood Flow Velocity |
| Zdroj: | Current rheumatology reports. 2(2) |
| ISSN: | 1523-3774 |
| Popis: | This paper examines the use of neuroimaging to measure change in regional cerebral blood flow (rCBF) produced by pain in patients with fibromyalgia and in healthy individuals. Fibromyalgia patients differ from healthy persons in rCBF distribution in several brain structures involved in pain processing and pain modulation both at rest and during experimental pain induction. These abnormalities may contribute to abnormal pain sensitivity as well as the maladaptive pain behaviors that characterize many patients with fibromyalgia. We anticipate that future neuroimaging studies will enhance our understanding of abnormal pain sensitivity and of pain management interventions aimed at altering central nervous system function in patients with fibromyalgia. |
| Databáze: | OpenAIRE |
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