A Practical CEUS Thyroid Reporting System for Thyroid Nodules

Autor:	Jingliang Ruan, Xiaolin Xu, Yan Cai, Hongyan Zeng, Man Luo, Wenyue Zhang, Rongbin Liu, Peiliang Lin, Yangming Xu, Qiong Ye, Bing Ou, Baoming Luo
Rok vydání:	2022
Předmět:	Adult Male Biopsy Fine-Needle Humans Female Radiology Nuclear Medicine and imaging Thyroid Nodule Middle Aged Sensitivity and Specificity Retrospective Studies Ultrasonography
Zdroj:	Radiology. 305:149-159
ISSN:	1527-1315 0033-8419
DOI:	10.1148/radiol.212319
Popis:	Background The role of contrast-enhanced US (CEUS) in reducing unnecessary biopsies of thyroid nodules has received little attention. Purpose To construct and externally validate a thyroid imaging reporting and data system (TI-RADS) based on nonenhanced US and CEUS to stratify the malignancy risk of thyroid nodules. Materials and Methods This retrospective study evaluated 756 patients with 801 thyroid nodules who underwent nonenhanced US, CEUS, and fine-needle aspiration and received a final diagnosis from January 2018 to December 2019. Qualitative US features of the thyroid nodules were analyzed with univariable and multivariable logistic regression to construct a CEUS TI-RADS. The CEUS TI-RADS was validated with use of internal cross-validation and external validation. Results A total of 801 thyroid nodules in 590 female (mean age, 44 years ± 13) and 166 male (mean age, 47 years ± 13 [SD]) patients were included. Independent predictive US features included nodule composition at CEUS, echogenicity, nodule shape, nodule margin, echogenic foci, extrathyroidal extension, enhancement direction, peak intensity, and ring enhancement. The CEUS TI-RADS showed a higher area under the receiver operating characteristic curve of 0.93 (95% CI: 0.92, 0.95
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53b92170897e9b8293d7f0d0107ed2cc https://doi.org/10.1148/radiol.212319 Zobrazit plný text záznamu