Exploring the relation between preoperative physical functioning and the impact of major complications in patients following pancreatic resection
| Autor: | Nico L. U. van Meeteren, Bart C. Bongers, Cornelius H. C. Dejong, Sander M. J. van Kuijk, Christel A. Van Beijsterveld, Marcel den Dulk |
|---|---|
| Přispěvatelé: | MUMC+: TPZ Fysiotherapie (9), Epidemiologie, RS: CAPHRI - R3 - Functioning, Participating and Rehabilitation, Nutrition and Movement Sciences, RS: NUTRIM - R3 - Respiratory & Age-related Health, RS: NUTRIM - R1 - Obesity, diabetes and cardiovascular health, MUMC+: MA Heelkunde (9), RS: NUTRIM - R2 - Liver and digestive health, MUMC+: KIO Kemta (9), RS: CAPHRI - R2 - Creating Value-Based Health Care, Surgery |
| Rok vydání: | 2019 |
| Předmět: |
medicine.medical_specialty
EXTERNAL VALIDATION SURGERY Prehabilitation medicine.medical_treatment INTERNATIONAL STUDY-GROUP CLASSIFICATION MORBIDITY Pancreatectomy Postoperative Complications medicine Humans In patient Major complication Postoperative Period Aerobic capacity Hepatology business.industry Incidence (epidemiology) Gastroenterology Perioperative Pancreaticoduodenectomy Prognosis Surgery DEFINITION PREHABILITATION Elective Surgical Procedures PANCREATICODUODENECTOMY RISK-FACTORS business Complication |
| Zdroj: | HPB, 22(5), 716-727. ELSEVIER SCI LTD |
| ISSN: | 1477-2574 1365-182X |
| Popis: | BACKGROUND: This study aimed to evaluate the association between preoperative level of physical functioning and time to recovery of physical functioning, postoperative complications, and the impact of postoperative major complications in patients undergoing elective pancreatic resection. Additionally, prediction models to identify high-risk patients for developing a major complication were externally validated.METHODS: Perioperative data of patients who underwent pancreatic resection were analysed. Primary outcomes were time to recovery of physical functioning and postoperative major complications. Impact of a major complication was explored by evaluating its effect on time to recovery of physical functioning. Risk-prediction models were retrieved following a systematic review.RESULTS: Multivariable analysis (n = 63) showed that ASA grade III (OR 3.498) and preoperative platelet count (OR 1.005) were associated with major complications, whereas aerobic capacity (OR 0.347) was associated with time to recovery of physical functioning. Age, preoperative aerobic capacity, functional mobility, and perceived level of functional capacity were associated with the impact of a major complication. The AUC of two risk prediction models were 0.556 and 0.701.CONCLUSION: Preoperative parameters of physical function were associated with postoperative outcomes and may be useful in outcome prediction, although future approaches should not only register the incidence of major complications but also take the impact of a complication on a patient's physical functioning into account. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|