Preoperative identification of cytokeratin 19 status of hepatocellular carcinoma based on diffusion kurtosis imaging

Autor: Jiejun Chen, Dingxia Liu, Yixian Guo, Yunfei Zhang, Yinglong Guo, Mengmeng Jiang, Yongming Dai, Xiuzhong Yao
Rok vydání: 2022
Předmět:
Zdroj: Abdominal radiology (New York).
ISSN: 2366-0058
Popis: To explore the potential value of diffusion kurtosis imaging (DKI) for identification of cytokeratin 19 (CK19) status of HCCs.This study was approved by the local institute review board and written informed consent was obtained. 73 patients with pathologically confirmed HCCs were included in this prospective study. All the diffusion-weighted (DW) images were acquired using a 3.0-T MR scanner with 4 b-values (0, 800, 1500 and 2000 s/mmIncreased a-fetoprotein level (p = 0.021) and SIRThe decreased MD value derived from DKI is potential quantitative biomarker for predicting CK19-positive HCCs.
Databáze: OpenAIRE