The Occurrence of Graves Disease (Autoimmune Thyrotoxicosis) in Endocrinologists at the Mount Sinai Hospital in New York City From 1954 to 2011
| Autor: | Robert L. Segal, Sylvan Wallenstein |
|---|---|
| Rok vydání: | 2015 |
| Předmět: |
Adult
Male endocrine system medicine.medical_specialty Pediatrics Endocrinology Diabetes and Metabolism Graves' disease education Endocrinology Risk Factors Physicians Internal medicine medicine Humans Poisson Distribution Family history Aged business.industry Incidence (epidemiology) Thyroid General Medicine Middle Aged medicine.disease Graves Disease Hospitals Thyrotoxicosis medicine.anatomical_structure Female New York City Radioactive iodine business Autoimmune thyrotoxicosis Exact probability |
| Zdroj: | Endocrine Practice. 21:482-487 |
| ISSN: | 1530-891X |
| DOI: | 10.4158/ep14342.or |
| Popis: | Objective: We report on the unique occurrence of Graves disease (thyrotoxicosis) in 7 male endocrinologists at the Mount Sinai Hospital (MSH) in New York City, New York between 1954 and 2011. Methods: We followed the endocrinologists and fellows assigned to the division over a period of 57 years by survey and personal contact. In the statistical studies, we assumed that the number of cases had a Poisson distribution and computed the exact probability based on the expected values. Results: Seven male endocrinologists had proven thyrotoxicosis during or following their service in the Endocrine Division at MSH. Six had a family history of thyrotoxicosis. None had known iodine 131 (131-I) thyroid contamination. Conclusion: The incidence of thyrotoxicosis greatly exceeds the rate predicted. Postulated factors in the causation of this unique occurrence are discussed. Abbreviations: 131-I = iodine 131 MSH = Mount Sinai Hospital RAI = radioactive iodine TSH = thyroid-stimulating hormone |
| Databáze: | OpenAIRE |
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