Immunochemical Studies on Tobacco Mosaic Virus

Autor:	Saul Malkiel
Rok vydání:	1952
Předmět:	Immunology Immunology and Allergy
Zdroj:	The Journal of Immunology. 69:525-531
ISSN:	1550-6606 0022-1767
DOI:	10.4049/jimmunol.69.5.525
Popis:	Summary The rod of tobacco mosaic virus has been fractured by exposure to sonic radiations. Unfractured, intact tobacco mosaic virus recovered following this treatment exhibited identical serological findings as the control virus and therefore suffered no changes. Preparations of short rods obtained by the sonic treatment of tobacco mosaic virus showed an enhancement of the antibody combining capacity as compared to the control. This was due in part to the increment of exposed surface following sonic treatment and probably in part to the closer packing of antibody molecules on the smaller fragments. No changes in serological specificity nor the presence of any new antigenic determinants could be detected in the fractured particles of virus. This indicated that the new surfaces exposed possessed the same molecular configuration as the original surface.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53b013d3f9dc203b44994a41f01b77dd https://doi.org/10.4049/jimmunol.69.5.525 Zobrazit plný text záznamu