Sensitivity of Mouse Lymphoid and Nonlymphoid Organs to Silesian Air Pollutants
| Autor: | Ewa Kozlowska, Izdebska-Szymona K, Nadzieja Drela, J Kopeć-Szlezak, H. Michur |
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| Rok vydání: | 1997 |
| Předmět: |
Pathology
medicine.medical_specialty Ratón Health Toxicology and Mutagenesis Spleen Air Pollutants Occupational Thymus Gland Biology Kidney Mice Atrophy Air pollutants medicine Animals Lymphatic Diseases Mice Inbred BALB C Public Health Environmental and Occupational Health Histology Organ Size General Medicine medicine.disease Pollution Lymphatic system medicine.anatomical_structure Liver Immunology Toxicity Female Poland |
| Zdroj: | Ecotoxicology and Environmental Safety. 37:10-16 |
| ISSN: | 0147-6513 |
| DOI: | 10.1006/eesa.1996.1513 |
| Popis: | The toxic effect of Silesian air pollutants to mouse organs was examined. Histological changes were found in the examined lymphoid organs (thymus, spleen) as well nonlymphoid organs (liver, kidneys). The alterations in weight indexes of lymphoid organs were also observed. Considerable changes in cellularity, weight index, and histology of the thymus in the mice exposed to air pollutants suggest the atrophy of this organ, which may lead to extrathymic T-cell differentiation and even acceleration of thymocytes maturation, which may lead to certain allergic or autoimmune processes. The results suggest the sensitivity to Silesian air pollutants of all investigated mouse organs in the following order: thymus, liver, kidneys, and spleen. |
| Databáze: | OpenAIRE |
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