Reference values for serum lipids and lipoproteins in Spanish adolescents: the AVENA study
| Autor: | Fatima Perez de Heredia, Francisco B Ortega, Marta Garaulet, Francisca Pérez-Llamas, JONATAN RUIZ, Domingo Gonzalez-Lamuño, Pablo Tercedor, Angel Gutierrez Sainz, Julia Warnberg, Manuel Joaquin Castillo Garzon, J Alfredo Martínez Hernández, Palma Chillón, Marcela Gonzalez-Gross |
|---|---|
| Rok vydání: | 2006 |
| Předmět: |
Male
Percentile medicine.medical_specialty Adolescent Urban Population Apolipoprotein B Lipoproteins Blood lipids chemistry.chemical_compound Sex Factors High-density lipoprotein Reference Values Internal medicine medicine Humans Triglycerides Analysis of Variance Apolipoprotein A-I biology Triglyceride Cholesterol Cholesterol HDL Age Factors Public Health Environmental and Occupational Health Cholesterol LDL Lipids Cross-Sectional Studies Endocrinology chemistry Spain Data Interpretation Statistical Low-density lipoprotein Apolipoprotein B-100 biology.protein Female Lipoprotein(a) Lipoprotein |
| Zdroj: | Digital.CSIC. Repositorio Institucional del CSIC instname |
| ISSN: | 1420-911X 0303-8408 |
| DOI: | 10.1007/s00038-005-0021-9 |
| Popis: | Ruiz, J.R;Ortega, F. B.;Moreno, L. A.;Wärnberg, Julia; González-Gross, M.;Marcos, Ascensión; et al. Objectives: To provide current reference values for serum lipid and lipoprotein levels in Spanish adolescents according to age and sex. Methods: A cross sectional study conducted in five representative Spanish cities (Granada, Madrid, Murcia, Santander and Zaragoza) including a representative sample of 581 adolescents (299 male and 282 female), aged 13 to 18.5 years. Age- and sex-specific means, standard deviations and percentiles were determined for: Total (TC), high density lipoprotein (HDLc) and low density lipoprotein (LDLc) cholesterol, triglycerides, apolipoprotein A-1 and B-100, and lipoprotein(a). Results: The 90th percentile for TC was 4.95 mmol/L for males and 5.19 mmol/L for females. HDLc levels were significantly higher in females of all age groups. LDLc levels ranged from 2.32 to 2.54 mmol/ L in males and from 2.38 to 2.62 mmol/L in females, peaking at 13 years of age in both sexes. Triglyceride levels tended to increase gradually and to peak at 17 years of age for both sexes. Apolipoprotein A-1 and B-100 levels paralleled those of HDLc and LDLc values, respectively. The geometric mean for lipoprotein(a) levels ranged from 0.44 to 0.57 μmol/L in males and from 0.50 to 0.67 μmol/L in females. Conclusions: The present study provides reference data on the distribution of lipid and lipoprotein levels of Spanish adolescents. © Birkhäuser Verlag, Basel 2006. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full text from SpringerLink