Impact of second forward-view examination on adenoma detection rate during unsedated colonoscopy: a randomized controlled trial
| Autor: | Hongpeng Lu, Keshu Shan, Jiarong Xie, Lei Xu, Lu Xu, Zhixin Zhang, Chun-Jiu Hu, Weihong Wang |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Adenoma
medicine.medical_specialty Colorectal cancer Second forward-view examination Colonoscopy RC799-869 Gastroenterology Colonic polyps law.invention 03 medical and health sciences 0302 clinical medicine Randomized controlled trial law Internal medicine medicine Humans Prospective Studies medicine.diagnostic_test Lesion detection business.industry Research Significant difference General Medicine Hepatology Diseases of the digestive system. Gastroenterology medicine.disease 030220 oncology & carcinogenesis Colonic Neoplasms Polyp detection rate 030211 gastroenterology & hepatology Detection rate Colorectal Neoplasms business Adenoma detection rate |
| Zdroj: | BMC Gastroenterology, Vol 21, Iss 1, Pp 1-8 (2021) BMC Gastroenterology |
| Popis: | Objectives Colorectal cancer on the right side of the colon has been suggested to be harder to detect by colonoscopy. The aim of this study was to evaluate whether a second forward-view examination of the right side of the colon could increase the adenoma detection rate (ADR) and/or polyp detection rate (PDR). Methods This was a single-centre randomized controlled trial. Patients undergoing colonoscopy were recruited and randomly assigned to the second forward-view examination (SFE) group, in which the right side of the colon was examined twice or the traditional colonoscopy (TC) group in which the colonoscopy was performed in a standard manner. The primary outcome was the ADR of right colon. The overall PDR and ADR, PDR of the right colon, per-adenoma miss rate of the right colon, and advanced lesion detection rate were also recorded and compared. Results A total of 392 patients were included in the study (SFE group 197 vs. TC group 195). The ADR and PDR of the right colon in the SFE group were significantly higher than those in the TC group (ADR 10.7% vs. 5.1%; P = 0.042); PDR 17.8% vs. 9.7%, P = 0.021). No significant difference was found in overall PDR/ADR, or advanced lesion detection rate between the two groups. Conclusions This prospective controlled study revealed that a second forward-view examination could modestly increase the ADR and PDR of the right colon during unsedated colonoscopies. This simple, safe and time-effective technique might be recommended for routine unsedated colonoscopy. Trial registration: Clinical Trials.gov, NCT03619122. Registered on 7/8/2018. |
| Databáze: | OpenAIRE |
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