Forearm vasodilator responses to environmental stress and reactive hyperaemia are impaired in young South Asian men
| Autor: | Natalie G. Ormshaw, Rehan T. Junejo, Janice M. Marshall |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: |
0301 basic medicine
Bradycardia Forearm dilatation Male medicine.medical_specialty Physiology Vasodilation Hyperemia 030204 cardiovascular system & hematology 03 medical and health sciences FEV1/FVC ratio Hyperaemia Young Adult 0302 clinical medicine Forearm Asian People Stress Physiological Physiology (medical) Internal medicine Heart rate Medicine South Asian Humans Orthopedics and Sports Medicine Reactive hyperaemia business.industry Public Health Environmental and Occupational Health General Medicine Mental stress 030104 developmental biology Blood pressure medicine.anatomical_structure Regional Blood Flow Cardiology Original Article Endothelium Vascular medicine.symptom business Vasoconstriction |
| Zdroj: | European Journal of Applied Physiology EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY |
| ISSN: | 1439-6327 1439-6319 |
| Popis: | PurposePrevalence of cardiovascular disease (CVD) is greater in South Asians (SAs) than White Europeans (WEs). Endothelial dysfunction and blunted forearm vasodilatation to environmental stressors have been implicated in CVD. We investigated whether these features are present in young SA men.MethodsIn 15 SA and 16 WE men (19–23 years), we compared changes in forearm blood flow, arterial blood pressure (ABP), forearm vascular conductance (FVC), heart rate, and electrodermal resistance (EDR; sweating) following release of arterial occlusion (reactive hyperaemia endothelium-dependent) and 5 single sounds at 5–10 min intervals (stressors).ResultsAll were normotensive. Peak reactive hyperaemia was smaller in SAs than WEs (FVC increase: 0.36 ± 0.038 vs 0.44 ± 0.038 units;P P P ConclusionsEndothelium-dependent vasodilatation is blunted in young SA men. This could explain their impaired forearm vasodilatation and greater pressor responses to repeated environmental stressors, so predisposing SAs to hypertension and CVD. |
| Databáze: | OpenAIRE |
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