Prospective Multicenter Study of Pneumocystis jirovecii Colonization among Cystic Fibrosis Patients in France
| Autor: | Julia Salleron, Emilie Fréalle, Benoit Wallaert, Francisca Hernández-Hernández, Patrick Caneiro, Eduardo Dei-Cas, Isabelle Accoceberry, Laurence Delhaes, Jean-Philippe Bouchara, Isabelle Durand-Joly |
|---|---|
| Přispěvatelé: | Centre d’Infection et d’Immunité de Lille - INSERM U 1019 - UMR 9017 - UMR 8204 (CIIL), Institut Pasteur de Lille, Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lille-Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille)-Centre National de la Recherche Scientifique (CNRS), Service de Microbiologie [Lille], Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille), Universidad Nacional Autónoma de México = National Autonomous University of Mexico (UNAM), Service de biostatistiques, Université de Lille, Sciences et Technologies-Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille), Centre Hospitalier de Dunkerque, Groupe hospitalier Saint-André [Bordeaux], CHU Bordeaux [Bordeaux], Groupe d'Étude des Interactions Hôte-Pathogène (GEIHP), Université d'Angers (UA), Laboratoire de Parasitologie-Mycologie, Centre Hospitalier Universitaire d'Angers (CHU Angers), PRES Université Nantes Angers Le Mans (UNAM)-PRES Université Nantes Angers Le Mans (UNAM), Service de Pneumologie et Immuno-Allergologie [CHU LIlle], Pole Cardio-vasculaire et pulmonaire [CHU Lille], Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille)-Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille), Francisca Hernández-Hernández was supported by the Programa de Apoyos para la Superación del Personal Académico (DGAPA, National Autonomous University of Mexico). We thank PHRC 1902, Vaincre la mucoviscidose, Pfizer, for their financial support., Centre National de la Recherche Scientifique (CNRS)-Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille)-Université de Lille-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut Pasteur de Lille, Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP), Universidad Nacional Autónoma de México (UNAM), Univ Angers, Okina |
| Jazyk: | angličtina |
| Rok vydání: | 2012 |
| Předmět: |
Male
Cystic Fibrosis [SDV]Life Sciences [q-bio] Pneumocystis carinii medicine.disease_cause Cystic fibrosis Gastroenterology MESH: Genotype MESH: Pneumocystis carinii / isolation & purification Colonization Prospective Studies Mycological Typing Techniques Prospective cohort study 0303 health sciences MESH: France / epidemiology biology MESH: Molecular Typing MESH: Pneumocystis carinii / genetics Pneumocystis Infections [SDV] Life Sciences [q-bio] MESH: Pneumocystis Infections / epidemiology MESH: Young Adult Carrier State Female France Adult Microbiology (medical) medicine.medical_specialty Adolescent Genotype Mycology MESH: Pneumocystis Infections / microbiology Young Adult 03 medical and health sciences MESH: Pneumocystis carinii / classification Internal medicine MESH: Mycological Typing Techniques medicine Humans Pneumocystis jirovecii MESH: Carrier State / epidemiology MESH: Carrier State / microbiology MESH: Cystic Fibrosis / complications 030304 developmental biology MESH: Adolescent MESH: Humans 030306 microbiology Pseudomonas aeruginosa MESH: Adult medicine.disease biology.organism_classification MESH: Prospective Studies MESH: Male Molecular Typing Carriage Immunology MESH: Female |
| Zdroj: | Journal of Clinical Microbiology Journal of Clinical Microbiology, 2012, 50 (12), pp.4107-4110. ⟨10.1128/JCM.01974-12⟩ Journal of Clinical Microbiology, American Society for Microbiology, 2012, 50 (12), pp.4107-4110. ⟨10.1128/JCM.01974-12⟩ |
| ISSN: | 0095-1137 |
| DOI: | 10.1128/JCM.01974-12⟩ |
| Popis: | Pneumocystis carriage was detected in 12.5% of 104 cystic fibrosis (CF) patients during a prospective multicenter French study, with a prevalence of genotype 85C/248C and geographic variations. It was significantly associated with the absence of Pseudomonas aeruginosa colonization and a greater forced expiratory volume in 1 s. Results are discussed considering the natural history of CF. |
| Databáze: | OpenAIRE |
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