Death or hospitalization of patients on chronic hemodialysis is associated with a physician-based diagnosis of depression
| Autor: | S. Susan Hedayati, Paul L. Kimmel, Hayden B. Bosworth, Lynda A. Szczech, Carl F. Pieper, Libbie P. Briley, Richard Sloane |
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| Rok vydání: | 2008 |
| Předmět: |
Adult
Male medicine.medical_specialty medicine.medical_treatment 030232 urology & nephrology Interviews as Topic 03 medical and health sciences 0302 clinical medicine Renal Dialysis Internal medicine Physicians Epidemiology medicine Humans 030212 general & internal medicine Prospective Studies Prospective cohort study Intensive care medicine Dialysis Depression (differential diagnoses) Survival analysis Aged Proportional Hazards Models Depressive Disorder Proportional hazards model business.industry Hazard ratio Middle Aged Prognosis mortality Survival Analysis 3. Good health Death Hospitalization Nephrology depression dialysis Kidney Failure Chronic Female Hemodialysis business Follow-Up Studies |
| Zdroj: | Kidney International. 74(7):930-936 |
| ISSN: | 0085-2538 |
| DOI: | 10.1038/ki.2008.311 |
| Popis: | Depressive symptoms, assessed using a self-report type of questionnaire, have been associated with poor outcomes in dialysis patients. Here we determined if depressive disorders diagnosed by physicians are also associated with such outcomes. Ninety-eight consecutive patients on chronic hemodialysis underwent the Structured Clinical Interview for Diagnostic and Statistical Manual of Mental Disorders administered by a physician. Depression was diagnosed in about a quarter of the patients. Associations adjusted for age, gender, race, time on dialysis and co-morbidity were determined using survival analysis. Using time to event (death or hospitalization) models of analysis the hazard ratios were 2.11 and 2.07 in unadjusted and adjusted models respectively. The finding of poor outcome using a formal structured physician interview suggests that a prospective study is needed to determine whether treatment of depression affects clinical outcomes. |
| Databáze: | OpenAIRE |
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