Tick (Ixodes holocydus) paralysis in the dog – induction of immunity by injection of toxin
| Autor: | A. L. Neish, I.G. Wright, B. F. Stone |
|---|---|
| Rok vydání: | 1983 |
| Předmět: |
Tick
medicine.disease_cause Beagle Tick paralysis Dogs Ticks Immune system Immunity Paralysis medicine Animals Dog Diseases Arthropod Venoms Vaccines General Veterinary biology Antivenins Toxin Vaccination General Medicine Tick Toxicoses biology.organism_classification medicine.disease Tick Paralysis Antibody Formation Immunology Female Ixodes medicine.symptom |
| Zdroj: | Australian Veterinary Journal. 60:69-70 |
| ISSN: | 1751-0813 0005-0423 |
| DOI: | 10.1111/j.1751-0813.1983.tb05872.x |
| Popis: | SUMMARY Three beagle dogs were immunised against the paralysing effects of holocyclotoxin, using toxic extracts derived from salivary glands of the Australian paralysis tick, Ixodes holocydus. Upon subsequent challenge with four ED50, of toxin the animals were completely immune, whereas during the early stages 2 of 3 dogs became paralysed after injection with 0.5 ED50. Three immunised beagles, on which 15 I. holocydus ticks had fed, showed no symptoms but a control beagle became paralysed after 4 I. holocydus females fed on it. Treatment was instituted immediately upon the onset of clinical signs and the dog recovered uneventfully. |
| Databáze: | OpenAIRE |
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