| Autor: |
Myrlon M. Van Ravensteijn, Mark F. Timmerman, Ester A. G. Brouwer, Dagmar Else Slot |
| Rok vydání: |
2022 |
| Předmět: |
|
| Zdroj: |
Van Ravensteijn, M M, Timmerman, M F, Brouwer, E A G & Slot, D E 2022, ' The effect of omega-3 fatty acids on active periodontal therapy : A systematic review and meta-analysis ', Journal of Clinical Periodontology, vol. 49, no. 10, pp. 1024-1037 . https://doi.org/10.1111/jcpe.13680 |
| ISSN: |
1600-051X |
| DOI: |
10.1111/jcpe.13680 |
| Popis: |
Aim: “Host modulatory therapy” (HMT) with ω-3 fatty acids aims at reducing inflammation. With HMT as an adjunct, a better result of periodontal therapy is expected. The aim of this systematic review and meta-analysis (MA) was to examine the additional effect of ω-3 fatty acids to non-surgical periodontal therapy (SRP) on the probing pocket depth (PPD) and the clinical attachment level (CAL). Materials and Methods: MEDLINE-PubMed and Cochrane-CENTRAL libraries were searched up to January 2021 for randomized controlled trials in patients with chronic periodontitis, treated with SRP/placebo as controls and SRP/ω-3 fatty acids as the test group. Results: The search identified 173 unique abstracts, and screening resulted in 10 eligible publications. Descriptive analysis showed a significant effect on the PPD and CAL in favour of the groups with ω-3 fatty acids in the majority of comparisons. MA revealed that adjunctive use of ω-3 fatty acids to SRP resulted in 0.39 mm more PPD reduction (95% CI: −0.58; −0.21) and 0.41 mm more CAL gain (95% CI: −0.63; −0.19) than SRP alone. Conclusions: In patients with periodontitis, dietary supplementation with ω-3 fatty acids as an adjunct to SRP is more effective in reducing the PPD and improving the CAL than SRP alone. If SRP is indicated, the use of ω-3 fatty acids can be considered for a moderate extra added effect on PPD reduction and CAL gain. The strength of this recommendation is moderate. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
|
Plný text