Adult Patient Preferences for Long-Acting ADHD Treatments: A Discrete Choice Experiment
| Autor: | Cambron-Mellott, M Janelle, Mikl, Jaromir, Matos, Joana E, Erensen, Jennifer G, Beusterien, Kathleen, Cataldo, Marc J, Hallissey, Bernadette, Mattingly, Gregory W |
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| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_treatment
Population Psychological intervention Medicine (miscellaneous) Discrete choice experiment CNS stimulants choice behavior 03 medical and health sciences 0302 clinical medicine 050602 political science & public administration medicine Attention deficit hyperactivity disorder 030212 general & internal medicine education Pharmacology Toxicology and Pharmaceutics (miscellaneous) Original Research education.field_of_study business.industry Health Policy discrete choice experiment 05 social sciences medicine.disease Patient preference 0506 political science Stimulant attention deficit hyperactivity disorder Long acting Patient Preference and Adherence business Psychosocial patient preference Social Sciences (miscellaneous) Clinical psychology |
| Zdroj: | Patient preference and adherence |
| ISSN: | 1177-889X |
| Popis: | M Janelle Cambron-Mellott,1 Jaromir Mikl,2 Joana E Matos,1 Jennifer G Erensen,2 Kathleen Beusterien,1 Marc J Cataldo,2 Bernadette Hallissey,1 Gregory W Mattingly3– 5 1Kantar Health, New York, NY, USA; 2Purdue Pharma L.P./Adlon Therapeutics, L.P., Stamford, CT, USA; 3Department of Psychiatry, Washington University School of Medicine, St. Louis, MO, USA; 4Midwest Research Group, St. Charles, MO, USA; 5St. Charles Psychiatric Associates, St. Charles, MO, USACorrespondence: M Janelle Cambron-MellottKantar Health, 3 World Trade Center, 175 Greenwich Street, 35th Floor, New York, NY, 10007, USATel +1 212 706 3961Email janelle.cambron-mellott@kantar.comBackground and Objective: Treatment for attention deficit hyperactivity disorder (ADHD) requires a multifaceted approach including psychosocial interventions and pharmacological treatment. This study evaluates preferences for specific attributes associated with different long-acting stimulant treatment among US adults with ADHD.Methods: Patients completed an online, cross-sectional survey, incorporating a discrete choice experiment to assess preferences for attributes.Results: Analyses included 200 adults with ADHD (mean age 33.0 years; 60% self-reporting moderate severity); the mean (SD) Adult ADHD Self-Report Scale-v1.1 score was 45.9 (12.4). Overall, patients valued speed of onset most and risk of rebound least. Three population groups with distinct preferences were identified: side effect-driven (n=69, 35%), quick onset-driven (n=47, 24%) and quick onset and long duration-driven (n=84, 42%).Conclusion: This study shows differences in how adults with ADHD value and assess benefit-risk trade-offs when considering the desired attributes of stimulant treatments, highlighting the importance of patient-physician shared decision-making to optimize the desired benefits of individualized treatment.Keywords: attention deficit hyperactivity disorder, choice behavior, CNS stimulants, discrete choice experiment, patient preference |
| Databáze: | OpenAIRE |
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