Junin virus structural proteins
Autor: | Z M De Martínez Segovia, M I De Mitri |
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Rok vydání: | 1977 |
Předmět: |
Immunology
Microbiology Viral Proteins Viral envelope Virology RNA Viruses Polyacrylamide gel electrophoresis Arenaviruses New World Glycoproteins chemistry.chemical_classification biology Molecular mass Glycopeptides Carbohydrate biology.organism_classification Molecular biology Glycopeptide Nucleoprotein Molecular Weight chemistry Biochemistry Insect Science Junin virus Peptides Glycoprotein Research Article |
Zdroj: | Journal of Virology. 21:579-583 |
ISSN: | 1098-5514 0022-538X |
DOI: | 10.1128/jvi.21.2.579-583.1977 |
Popis: | Polyacrylamide gel electrophoresis of purified Junin virus revealed six distinct structural polypeptides, two major and four minor ones. Four of these polypeptides appeared to be covalently linked with carbohydrate. The molecular weights of the six proteins, estimated by coelectrophoresis with marker proteins, ranged from 25,000 to 91,000. One of the two major components (number 3) was identified as a nucleoprotein and had a molecular weight of 64,000. It was the most prominent protein and was nonglycosylated. The other major protein (number 5), with a molecular weight of 38,000, was a glucoprotein and a component of the viral envelope. The location on the virion of three additional glycopeptides with molecular weights of 91,000, 72,000, and 52,000, together with a protein with a molecular weight of 25,000, was not well defined. |
Databáze: | OpenAIRE |
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