Prevention of Perinatal Hepatitis B Virus Transmission in an Obstetric/Infant Population
| Autor: | Gyorkos Tw, Joseph Dylewski, Elaine D Franco, Arvind K Joshi, Paul J Parker |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 1993 |
| Předmět: |
Microbiology (medical)
HBsAg Pediatrics medicine.medical_specialty education.field_of_study Virus transmission business.industry Population education Retrospective cohort study Prenatal care Hepatitis B medicine.disease lcsh:Infectious and parasitic diseases Perinatal hepatitis medicine Seroprevalence Original Article lcsh:RC109-216 business |
| Zdroj: | Canadian Journal of Infectious Diseases, Vol 4, Iss 5, Pp 288-291 (1993) |
| ISSN: | 1180-2332 |
| Popis: | Study Design: This retrospective study reviewed the screening practice and seroprevalence of hepatitis B surface antigen (HBsAg) among all mothers with live births at a teaching hospital in Montreal between November 1, 1990 and April 30, 1991.Results: Most women (94%) were screened prenatally and 5.2% postnatally. Screening status could not be determined for 0.8% of women. One-quarter of all postnatal screening results were available only at 48 h or more postdelivery. No infants born to women with postnatal screening or to women with unknown screening status were immunized expectantly. The maternal seroprevalence was 1.08% (95% confidence interval from 0.6, 1.4). All 22 infants born to HBsAg-positive mothers had received hepatitis B immune globulin within 12 h of birth and the first dose of hepatitis B vaccine within 24 h. Follow-up of infants revealed that only 50% had received the second and third doses according to the recommended protocol, with 83% completing the immunization series.Conclusion: These results indicate that a program of prenatal HBsAg screening and neonatal prophylaxis against hepatitis B can be successfully instituted in a high volume obstetric hospital, and that better monitoring of infants is required to ensure completion of vaccination. |
| Databáze: | OpenAIRE |
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