Pyrazinamide-induced granulomatous hepatitis
| Autor: | George Buyanowsky, Knobel B, Michael Dan, Liliana Zaidel |
|---|---|
| Rok vydání: | 1997 |
| Předmět: |
Male
Pathology medicine.medical_specialty Biopsy Antitubercular Agents Gastroenterology Liver Function Tests Internal medicine Isoniazid Medicine Humans Hyperuricemia Tuberculosis Pulmonary Hepatitis Granuloma medicine.diagnostic_test business.industry Pyrazinamide Middle Aged medicine.disease Hectic fever Liver Liver biopsy Granulomatous Hepatitis Etiology Chills Drug Therapy Combination medicine.symptom Chemical and Drug Induced Liver Injury business medicine.drug |
| Zdroj: | Journal of clinical gastroenterology. 24(4) |
| ISSN: | 0192-0790 |
| Popis: | Noncaseating granulomatous hepatitis may be caused by a variety of drugs, but we have not found, by computer search of the literature, a previous describe of granulomatous hepatitis associated with pyrazinamide. We describe a 52-year-old man with hectic fever, chills, extreme fatigue, liver damage, and hyperuricemia about 4 weeks after commencing pyrazinamide therapy. A liver biopsy specimen showed noncaseating epithelioid granulomas. The patient recovered soon after the interruption of tuberculostatic treatment. |
| Databáze: | OpenAIRE |
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