Evidence of Artemisinin-Resistant Malaria in Africa
| Autor: | Osbert T. Katuro, Emmanuel I. Odongo-Aginya, Sakurako Emoto, Shin-Ichiro Tachibana, Nirianne Marie Q. Palacpac, Martin D. Ogwang, Eisaku Kimura, Toshihiro Mita, Naoyuki Fukuda, Masato Yamauchi, Mie Ikeda, Denis A Anywar, Betty Balikagala, Walter Opio, Toshihiro Horii |
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| Rok vydání: | 2021 |
| Předmět: |
Plasmodium falciparum
Drug Resistance Protozoan Proteins chemical and pharmacologic phenomena Southeast asian Polymorphism Single Nucleotide Antimalarials parasitic diseases medicine Humans Uganda Longitudinal Studies Artemisinin Malaria Falciparum biology Traditional medicine business.industry General Medicine medicine.disease biology.organism_classification Artemisinins Mutation business Malaria medicine.drug |
| Zdroj: | The New England journal of medicine. 385(13) |
| ISSN: | 1533-4406 |
| Popis: | In the six Southeast Asian countries that make up the Greater Mekong Subregion,In this longitudinal study conducted in Northern Uganda, we treated patients who hadFrom 2017 through 2019, a total of 14 of 240 patients who received intravenous artesunate had evidence of in vivo artemisinin resistance (parasite clearance half-life,5 hours). Of these 14 patients, 13 were infected withThe independent emergence and local spread of clinically artemisinin-resistant |
| Databáze: | OpenAIRE |
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