The association between retinal nerve fibre layer thickness and corpus callosum index in different clinical subtypes of multiple sclerosis
| Autor: | Vedat Cilingir, Abdullah Yılgör, Temel Tombul, Tekin Yaşar, Aysel Milanlioglu, Mehmet Deniz Bulut, Abdussamet Batur, Muhammed Batur |
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| Rok vydání: | 2017 |
| Předmět: |
Adult
Male Retinal Ganglion Cells medicine.medical_specialty Pathology Multiple Sclerosis Optic Neuritis Neurology genetic structures Dermatology Corpus callosum Corpus Callosum 03 medical and health sciences chemistry.chemical_compound Nerve Fibers 0302 clinical medicine Atrophy Ophthalmology medicine Humans Optic neuritis Neuroradiology medicine.diagnostic_test Multiple sclerosis Magnetic resonance imaging Retinal General Medicine Middle Aged medicine.disease Axons eye diseases Psychiatry and Mental health chemistry 030221 ophthalmology & optometry Female sense organs Neurology (clinical) Psychology Tomography Optical Coherence 030217 neurology & neurosurgery |
| Zdroj: | Neurological Sciences. 38:1223-1232 |
| ISSN: | 1590-3478 1590-1874 |
| Popis: | The objective of this paper is to evaluate the association between physical disability in multiple sclerosis (MS) patients, the thickness of the retinal nerve fibre layer (RNFL) and corpus callosum volumes, as expressed by the corpus callosum index (CCI). This study was based on a cohort of 212 MS patients and 52 healthy control subjects, who were age and gender matched. The MS patients included 144 women and 177 relapsing-remitting MS (RRMS) patients. Peripapillary and volumetric optical coherence tomography (OCT) scans of the macula were performed using spectral-domain OCT technology. All magnetic resonance imaging (MRI) scans were performed using 1.5-T systems. CCI and RNFL were lower in MS than healthy control subjects (0.341 versus 0.386, p |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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