Prospective Trial of Computer Program for the Diagnosis of Thyroid Disorders
| Autor: | C. M. Boyd, John Stiel, M. J. Hooper, T. H. Oddie, I. B. Hales, Thomas S. Reeve, D. A. Fisher |
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| Rok vydání: | 1974 |
| Předmět: |
endocrine system
medicine.medical_specialty endocrine system diseases Biopsy Endocrinology Diabetes and Metabolism Clinical Biochemistry Population Biochemistry Endocrinology Internal medicine Methods medicine Humans Diagnosis Computer-Assisted Prospective Studies Prospective cohort study Chronic thyroiditis education Thyroid cancer Probability Subacute thyroiditis education.field_of_study medicine.diagnostic_test business.industry Incidence (epidemiology) Biochemistry (medical) Thyroid medicine.disease Thyroid Diseases medicine.anatomical_structure business |
| Zdroj: | The Journal of Clinical Endocrinology & Metabolism. 38:876-882 |
| ISSN: | 1945-7197 0021-972X |
| DOI: | 10.1210/jcem-38-5-876 |
| Popis: | A computer program, developed to help in the diagnosis of thyroid disorders, has been operated routinely in a general thyroid clinic. Diagnostic probabilities were computed from relevant signs, symptoms and test results using Bayes' theorem. In a prospective trial with 1,200 consecutive new patients entering the clinic the program performed very satisfactorily in classifying metabolic status (99.1% correct). In deciding about other thyroid disorders before biopsy neither the physicians (41.4% correct) nor the computer (34.5% correct) were very successful. Better tests and statistics, are expected to improve these results. In this (Sydney, Australia) clinic population the estimated percent incidence of thyroid disorders was: hypothyroidism 2.7%; hyperthyroidism 10.0%; subacute thyroiditis 0.92%; chronic thyroiditis, non-specific 0.38%, Hashimoto's 2.63%; thyroid cancer 1.00%, abnormal synthesis 0.08%. For 19/2, the mean iodine intake for female patients in Sydney was computed to be 242 μg/day. |
| Databáze: | OpenAIRE |
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