B Virus (Herpesvirus simiae) Infection in Humans: Epidemiologic Investigation of a Cluster
| Autor: | Michael R. Ball, Jonathan E. Kaplan, George S. Ward, Gary P. Holmes, Christine M. Schindler, James A. Brady, Angus H. Rupert, Karl C. Klontz, Eva Parrish, Terrell W. Bean, Michael H. Wilder, Norman D. Bernstein, D. Gary Griffin, Julia K. Hilliard |
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| Rok vydání: | 1990 |
| Předmět: |
Adult
Male Herpes B virus Herpesvirus 1 Cercopithecine Disease cluster Virus Zoonoses Internal Medicine Animals Cluster Analysis Humans Medicine Bites and Stings Animal Husbandry Encephalomyelitis biology Transmission (medicine) business.industry Herpesviridae Infections General Medicine Middle Aged biology.organism_classification Macaca mulatta Virology Topical medication Occupational Diseases Acute Disease Immunology Protective gear Florida Female business Contact tracing Autoinoculation |
| Zdroj: | Annals of Internal Medicine. 112:833 |
| ISSN: | 0003-4819 |
| Popis: | A cluster of four cases of symptomatic B virus infection in humans occurred in Pensacola, Florida, in March 1987. Three cases occurred in persons who worked with monkeys at a research facility, and the fourth resulted from apparent autoinoculation through use of a nonprescription skin cream. Contact tracing identified 159 persons who may have been exposed to B virus (21 had been exposed to monkeys at the facility and 138 had been exposed to one or more of the case-patients), but no further cases were identified. Comparisons of restriction endonuclease patterns from B virus isolates linked two of the three cases in monkey handlers to one clinically ill monkey and the other to a second, healthy monkey. Three risk factors for human infection were identified: nonuse of mechanical or chemical restraints for monkeys before handling, nonuse of available protective gear, and direct viral inoculation through the application of a topical medication. |
| Databáze: | OpenAIRE |
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