Synthetic Studies toward Lapidilectine-Type Kopsia Alkaloids
| Autor: | Richmond Sarpong, Erica E. Schultz, Brian G. Pujanauski |
|---|---|
| Rok vydání: | 2012 |
| Předmět: |
Indole test
Indoles Lactams Molecular Structure biology Apocynaceae Extramural Chemistry Stereochemistry Organic Chemistry Lapidilectine B Stereoisomerism Oxidation reduction biology.organism_classification Biochemistry Article Indole Alkaloids Alkaloids Organic chemistry Spiro Compounds Kopsia Physical and Theoretical Chemistry Oxidation-Reduction |
| Zdroj: | Organic Letters. 14:648-651 |
| ISSN: | 1523-7052 1523-7060 |
| DOI: | 10.1021/ol203302f |
| Popis: | A rapid synthesis of the tetracyclic core of Kopsia indole alkaloids related to lapidilectine B, grandilodine C, and tenuisine A is reported. Key to the success of this route was an efficient and scalable Ugi four-component coupling to install all the necessary carbons found in the natural products. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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