Clinical predictors of intractable childhood epilepsy
| Autor: | Joseph Hertecant, László Sztriha, Aithala Gururaj, Valsamma Eapen |
|---|---|
| Rok vydání: | 2006 |
| Předmět: |
Male
Pediatrics medicine.medical_specialty Adolescent United Arab Emirates Neurological disorder Severity of Illness Index Epilepsy Catchment Area Health Predictive Value of Tests Severity of illness medicine Humans Prospective Studies Generalized epilepsy Age of Onset Prospective cohort study Child Demography business.industry Case-control study Brain Infant Electroencephalography medicine.disease Psychiatry and Mental health Clinical Psychology El Niño Child Preschool Female Age of onset business |
| Zdroj: | Journal of psychosomatic research. 61(3) |
| ISSN: | 0022-3999 |
| Popis: | This study aimed to determine the clinical, electroencephalographic, and radiological factors associated with medically intractable seizures in children in the Al Ain Medical District in the United Arab Emirates.This work used a prospective case-control study of children referred to pediatric neurology and neurodevelopmental clinics at Tawam and Al Ain University Hospitals.There were 55 children with intractable epilepsy; their data were compared with 50 children who responded well to antiepileptic drugs and who were seizure-free for at least 2 years. Onset1 year of age, a high seizure frequency at onset, positive history of neonatal seizures, developmental delay and status epilepticus, neurological deficits, and abnormal brain imaging results were found to be significantly more common in the study group. Symptomatic localization-related epilepsy was more common in children in this group than in the control group.Our study suggests that children who present with idiopathic localization-related and generalized epilepsy syndromes with few seizures at onset and with no neurological deficits tend to have a relatively good prognosis. |
| Databáze: | OpenAIRE |
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