Review on analytical studies of some pharmaceutical compounds containing heterocyclic rings: brinzolamide, timolol maleate, flumethasone pivalate, and clioquinol
| Autor: | Nada Nabil, Hala E. Zaazaa, Asmaa A. Mandour, Mohamed Abdelkawy |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Antifungal
medicine.drug_class Brinzolamide lcsh:RS1-441 010402 general chemistry 01 natural sciences High-performance liquid chromatography lcsh:Pharmacy and materia medica medicine Timolol maleate Chromatography Flumethasone pivalate Chemistry Clioquinol Heterocyclic lcsh:RM1-950 010401 analytical chemistry 0104 chemical sciences lcsh:Therapeutics. Pharmacology Antiprotozoal HPLC Quantitative analysis (chemistry) medicine.drug |
| Zdroj: | Future Journal of Pharmaceutical Sciences, Vol 6, Iss 1, Pp 1-10 (2020) |
| ISSN: | 2314-7253 |
| DOI: | 10.1186/s43094-020-00068-4 |
| Popis: | BackgroundThe heterocyclic compounds are extremely important with wide array of synthetic, pharmaceutical, and industrial applications. Heterocyclic-containing compounds have been reported for their broad spectrum of biological activities including antibacterial, antifungal, antiviral, antiprotozoal, and anthelmintic activity.Main textSeveral techniques have been used for the quantitation of heterocyclic compounds in pharmaceutical samples such as high-performance liquid chromatography (HPLC) either equipped with UV-visible or fluorescence, in addition to liquid chromatography-mass spectroscopy, UV-visible spectrophotometry, and electrochemical techniques. This article reviewed several published methods that have been applied to detect and quantify some pharmaceutical drugs containing heterocyclic compounds focusing on four drugs: brinzolamide, timolol maleate, flumethasone pivalate, and clioquinol.ConclusionFrom literature reviews, HPLC is the most widely used analytical technique for the quantitative analysis of the four selected drugs. |
| Databáze: | OpenAIRE |
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