The Neuroprotective and Neurotrophic Effects ofTremella fuciformisin PC12h Cells
| Autor: | Kenzo Chiba, Hyo Cheol Ha, Hyun Su Kim, Sang-Yun Lee, Kum Ju Park, Matsumi Yamazaki |
|---|---|
| Rok vydání: | 2007 |
| Předmět: |
chemistry.chemical_classification
Tremella fuciformis biology Neurite PC12h cell Active domain Neurotrophic effect Peptide Pharmacology biology.organism_classification Microbiology Neuroprotection Infectious Diseases chemistry Neuroprotective effect Toxicity biology.protein Potency Research Article Neurotrophin |
| Zdroj: | Mycobiology |
| ISSN: | 1229-8093 |
| Popis: | We examined the neuroprotective and neurotrophic effects of Tremella fuciformis. The neurotrophic effects of the hot water extract of T. fuciformis was evaluated by microscopically monitoring its potency to induce neurite outgrowth in PC12h cells. The hot water extract of T. fuciformis promoted neurite outgrowth in PC12h cells in this study, superior to other natural substances which was reported previously. When cells were treated with the hot water extract of T. fuciformis prior to β-amyloid peptide treatment (active domain of A peptide 25~35 treated), toxicity was significantly diminished (p |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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