Kleine-Levin syndrome related to pregnancy: a case report

Autor:	Hrayr Attarian, Samson G. Khachatryan, Lusine V. Vardanyan, Laura G. Khachatryan, Alejandra Lastra
Rok vydání:	2021
Předmět:	Pulmonary and Respiratory Medicine Pediatrics medicine.medical_specialty Pregnancy business.industry Case Reports medicine.disease medicine.disease_cause Pathophysiology Autoimmunity Neurology Kleine–Levin syndrome Menstrual related hypersomnia Medicine Neurology (clinical) business
Zdroj:	J Clin Sleep Med
ISSN:	1550-9397 1550-9389
Popis:	Kleine-Levin syndrome (KLS) is a rare disorder of recurrent hypersomnolence. The pathophysiology continues to be poorly understood. Autoimmunity, genetic polymorphisms, dysfunction of the hypothalamic axis, and abnormalities in functional imaging have been proposed. Several triggers have been described, including infection, toxins, head trauma, sleep deprivation, lactation, and menses. We present the first case report in the medical literature of KLS triggered by pregnancy and the first case of KLS from Armenia. Our patient has a pattern of mostly pregnancy-related episodes of several day sleepiness occurring monthly. This case adds to the published literature as we present a new association and explore the pathophysiology of KLS. CITATION: Khachatryan SG, Lastra AC, Vardanyan LV, Khachatryan LG, Attarian HP. Kleine-Levin syndrome related to pregnancy: a case report. J Clin Sleep Med. 2021;17(11):2325–2327.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5349f7f265114341ff2e082b5e26589d https://doi.org/10.5664/jcsm.9482 Zobrazit plný text záznamu