Multiple Hip Intra-Articular Steroid Injections Increase Risk of Periprosthetic Joint Infection Compared With Single Injections
| Autor: | Andrew A. Freiberg, Ming Han Lincoln Liow, Andrew W. Chambers, Young-Min Kwon, John Paul M. Manalo, Kyle W. Lacy |
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| Rok vydání: | 2016 |
| Předmět: |
musculoskeletal diseases
Male medicine.medical_specialty Prosthesis-Related Infections Arthroplasty Replacement Hip Periprosthetic Osteoarthritis Hip Injections Intra-Articular 03 medical and health sciences 0302 clinical medicine Intra articular Diabetes mellitus Medicine Humans Orthopedics and Sports Medicine Aged Retrospective Studies 030203 arthritis & rheumatology 030222 orthopedics Arthritis Infectious business.industry Odds ratio Middle Aged medicine.disease Surgery Increased risk Matched group Female Steroids business Body mass index Total hip arthroplasty |
| Zdroj: | The Journal of arthroplasty. 32(6) |
| ISSN: | 1532-8406 |
| Popis: | Background Patients with hip osteoarthritis often temporize their symptoms with multiple intra-articular steroid hip injections (IASHIs) before undergoing total hip arthroplasty (THA). Although there is recent evidence to suggest that IASHI can lead to an increased risk of future periprosthetic joint infection (PJI), the potential increase in risk of PJI after multiple IASHIs compared with single IASHI remains largely unknown. The aim of the study was to evaluate whether multiple IASHIs are associated with increased risk of PJI compared with single IASHI in THA patients. Methods We evaluated 2 cohorts of patients consisting of 106 patients who received 2 or more IASHI in the year before THA and a matched group of 350 patients who received one IASHI in the 12 months before THA. Results The single and multiply-injected patient cohorts had an infection rate of 2.0% and 6.6% (7/350 and 7/106), respectively ( P = .04, odds ratio 3.30) and average follow-up of 28.9 and 24.2 months. The 2 cohorts did not differ with regard to age, gender, American Society of Anesthesiologist score, presence of diabetes mellitus, or body mass index. Conclusion In comparison with patients with single IASHI, multiple IASHIs are associated with an increased risk of PJI significantly higher than the elevated risk reported with single injection before THA. The present study findings would be clinically useful in counseling patients who are considering temporizing their symptoms with multiple IASHIs before undergoing THA. |
| Databáze: | OpenAIRE |
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