Interactions of Selenium and Fluoride on Growth, Glycolysis and Survival of Streptococcus mutans GS-5
| Autor: | M.E.J. Curzon, A.D. Eisenberg, E.J. Izaguirre-Fernández |
|---|---|
| Rok vydání: | 1990 |
| Předmět: |
Colony Count
Microbial Dental Plaque chemistry.chemical_element Selenious Acid Streptococcus mutans Fluorides Selenium chemistry.chemical_compound Organoselenium Compounds Animals Drug Interactions Glycolysis General Dentistry Cell yield Volume concentration biology Hydrogen-Ion Concentration biology.organism_classification Rats On cells chemistry Biochemistry Cystine Antibacterial action Fluoride |
| Zdroj: | Caries Research. 24:306-311 |
| ISSN: | 1421-976X 0008-6568 |
| Popis: | The effects of low concentrations (1.0 mmol/l of selenite and seleno-dl-cystine were tested alone, or in combination with NaF, on growth, glycolysis, and survival of Streptococcus mutans GS-5. In batch culture, both selenium-containing compounds (1.0 mmol/l) inhibited the growth rate and final cell yield by 92% or greater; glycolysis, however, was not affected. The observed bactericidal action of selenite at 0.1 mmol/l was pH-dependent. Fluoride reduced the killing effect of SeO3 in the culture medium and in a lactate-acetate buffer system at pH 6.5, 5.0 and 4.0. These data indicate that selenium-containing compounds exert an antibacterial action on cells of S. mutans in a manner which leaves glycolysis unaffected. |
| Databáze: | OpenAIRE |
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