Different Materials for Plugging a Dehiscent Superior Semicircular Canal: A Comparative Histologic Study Using a Gerbil Model
| Autor: | Jürgen Strutz, Otto Gleich, Pingling Kwok, Thilo Spruss |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
Autophony
Male Artificial bone Bone wax Hearing Loss Conductive Dentistry Dehiscence Gerbil Mastoid 03 medical and health sciences 0302 clinical medicine Adhesives Surgical Wound Dehiscence otorhinolaryngologic diseases medicine Animals 030223 otorhinolaryngology Polytetrafluoroethylene Wax Bone Transplantation Semicircular canal business.industry Muscles medicine.disease Sensory Systems Semicircular Canals Conductive hearing loss medicine.anatomical_structure Otorhinolaryngology Adipose Tissue visual_art Waxes visual_art.visual_art_medium sense organs Neurology (clinical) business Gerbillinae Otologic Surgical Procedures 030217 neurology & neurosurgery |
| Zdroj: | Otologyneurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology. 40(5) |
| ISSN: | 1537-4505 |
| Popis: | Hypothesis: The choice of the material for plugging a dehiscence of the superior semicircular canal is based on the ease of use and the success of the procedure to permanently relieve symptoms without adverse side effects. Background: Dehiscence of the superior semicircular canal can lead to autophony, conductive hearing loss, and vertigo. Surgical treatment by plugging the canal is a highly effective treatment of the symptoms in many patients, although, the procedure can be associated with some degree of hearing loss in more than or equal to 25% of the patients. The available data indicate that adverse effects may be more frequently observed with bone wax as compared with other materials. Methods: In the present study we compare the tissue reactions induced by plugging the superior semicircular canal with autologous bone pate/bone chips, muscle, fat, artificial bone wax, and teflon in the gerbil model in an attempt to identify the material leading to successful plugging with the least adverse tissue reactions. Results: Our data show that successful plugging was achieved in 100% of the ears by bone pate/bone chips, teflon, and bone wax while the success rate was significantly lower ( |
| Databáze: | OpenAIRE |
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