Effects of stellate ganglion block on healing of fractures induced in rats
| Autor: | A. Alper Sahin, Husamettin Cakici, Erkan Kilinc, Tulin Firat, Hasan Kizilay, Tolgahan Kuru |
|---|---|
| Přispěvatelé: | BAİBÜ, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Fırat, Tülin, Çakıcı, Hüsamettin, Kılınç, Erkan |
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
Cartilage
Articular Male medicine.medical_specialty Article Subject Stellate Ganglion Bone healing General Biochemistry Genetics and Molecular Biology Bone remodeling 03 medical and health sciences 0302 clinical medicine Forearm Osteogenesis Forelimb Medicine Animals Stellate ganglion block Fractures Closed Rats Wistar Immature Bone Acetaminophen Stellate Ganglion Block 030203 arthritis & rheumatology Fracture Healing 030222 orthopedics General Immunology and Microbiology business.industry Cartilage General Medicine Anatomy Analgesics Non-Narcotic medicine.anatomical_structure Stellate ganglion Orthopedic surgery business Research Article Autonomic Nerve Block |
| Zdroj: | BioMed Research International BioMed Research International, Vol 2020 (2020) |
| Popis: | Objective. Sympathetic blocks are used as an adjunct for pain management in the treatment of orthopedic and traumatic conditions. Stellate ganglion (ganglion stellatum) provides sympathetic innervation of the head, neck and cervicothoracic regions, and upper extremities. No study was found in the literature investigating the effects of stellate ganglion block performed in the upper extremity, on blood supply to bone, density, vascularization, and bone metabolism. Therefore, the objective of this study was to investigate the effects of stellate ganglion block on healing of closed forearm fractures that were induced in rats.Material and Methods. A total of 42 Wistar albino rats weighing between 398 and 510 g were used in this study. The rats were randomly divided into 2 groups with one group treated with stellate ganglion and the other included as the control group. In each 2 groups, a closed forearm fracture was created, confirmed with X-ray, and then stabilized by splint application. The forearm bones were examined with X-ray views on the same day and were then decalcified.Results. When histological findings of the fracture region were examined, predominantly cartilage and less woven bone were found in 7 rats, equally distributed cartilage and immature bone in 14 rats, and predominantly imitation bone and less cartilage formation in 21 rats. In the control group, the agreement between the 1st and 2nd orthopedists for the radiological evaluation of bone formation was moderate.Conclusion. The group administered stellate ganglion block showed a more significant fracture healing. |
| Databáze: | OpenAIRE |
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