Robotically assisted laparoscopic radical prostatectomy induces lower tissue trauma than radical retropubic prostatectomy

Autor: Carlo C. Passerotti, Denise Quinto, José Arnaldo Shiomi da Cruz, Miguel Srougi, Hamilton Zampolli, Katia R. M. Leite, Nayara I. Viana, Ruan Pimenta, Vanessa Ribeiro Guimarães, Mario P Gimenez, Gabriel Arantes Dos Santos, Sabrina T. Reis, Lucca Juvele Zampolli
Rok vydání: 2020
Předmět:
Zdroj: Journal of Robotic Surgery. 15:147-151
ISSN: 1863-2491
1863-2483
DOI: 10.1007/s11701-020-01150-y
Popis: To compare tissue trauma between Retropubic Radical Prostatectomy and Robotically Assisted Laparoscopic Radical Prostatectomy by inflammatory mediators. Serum samples from 40 patients submitted to RALP and 20 patients submitted to RRP were withdrawn at four different time points. The cytokines IL-4, IL-8, IL-6, IL-1B, IL-10 and TNF-α were detected using ELISA/Multiplex assays and xMAP-Luminex®. With both techniques, IL-10 and IL-6 were higher in T4 than in T1-T3 (p = 0.001). IL-10 and IL-6 were higher in T4 in open surgery than in robotic surgery (p = 0.000 and p = 0.001, respectively). Compared with both groups, IL-6 and IL-10 were higher in T4 in open surgery than in robotic surgery. Thus, we can postulate that RALP causes less tissue trauma than classical RRP, as indicated by the more limited increase in inflammatory mediators such as IL-6 and IL-10.
Databáze: OpenAIRE
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