Long‐term mortality, disability and stroke recurrence in patients with basilar artery occlusion

Autor: Eelco F. M. Wijdicks, Elena Blaginykh, Maximiliano A. Hawkes, Tamika M. Burrus, Alejandro A. Rabinstein, Michael W. Ruff
Rok vydání: 2019
Předmět:
Zdroj: European Journal of Neurology. 27:579-585
ISSN: 1468-1331
1351-5101
DOI: 10.1111/ene.14126
Popis: BACKGROUND AND PURPOSE The long-term outcomes and stroke recurrence after basilar artery occlusion (BAO) are largely unknown. We aimed to assess these variables in a comparatively large series of consecutive patients. METHODS Adults with acute BAO were retrospectively identified from 1976 to 2011. Post-discharge records were reviewed to assess for stroke recurrences, mortality and disability. Exploratory analysis of survival was carried out using Kaplan-Meier and log-rank tests. Factors associated with survival time were determined using Cox models. RESULTS A total of 86 patients (34% female, median age 72 [interquartile range (IQR), 60-79] years) with a median National Institutes of Health Stroke Scale score of 11 (IQR, 6-27) were included. Twenty-nine patients (34%) died during the initial hospitalization. Median modified Rankin Scale (mRS) score at discharge among survivors was 4 (IQR, 2.5-5.5). At 1 and 5 years, 70% of survivors ad a mRS ≤3. Seventeen patients had recurrent strokes during the hospitalization and 12 patients had 19 recurrent strokes after discharge. The median survival time was 52 days (IQR, 6-1846). Older age per decade on admission [adjusted hazard ratios (aHR), 1.32; 95% confidence interval (CI), 1.05-1.66, P = 0.02] and a higher mRS at discharge (aHR, 4.48; 95% CI, 2.72-7.39, P
Databáze: OpenAIRE
Externí odkaz: