Mediterranean diet and risk of pancreatic cancer in the European Prospective Investigation into Cancer and Nutrition cohort
Autor: | Guri Skeie, Petra H.M. Peeters, Khalid Iqbal, José María Huerta, Aurélie Affret, Ruth C. Travis, Amanda J. Cross, Rosario Tumino, Kim Overvad, María José Sánchez, Inge Huybrechts, José Ramón Quirós, Weimin Ye, Marie-Christine Boutron-Ruault, Genevieve Buckland, Elio Riboli, Salvatore Panico, Esther Molina-Montes, Pilar Amiano, Eric J. Duell, Kay-Tee Khaw, Nicholas J. Wareham, Mathilde His, Heather Ward, Heinz Freisling, Tilman Kühn, Antonia Trichopoulou, Hendrik B. Bueno-de-Mesquita, Domenico Palli, Elisabete Weiderpass, Effie Vasilopoulou, Anne Tjønneland, Kristina E.N. Petersen, Verena Katzke, Emily Sonestedt, Claudia Agnoli, Christina Bamia, Bodil Ohlsson, Heiner Boeing, Petra A. Wark, Malin Sund, Eva Ardanaz, Carlotta Sacerdote |
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Přispěvatelé: | University Medical Center Utrecht, Imperial College Trust, Molina Montes, Esther, Sánchez, María José, Buckland, Genevieve, Bueno de Mesquita, H. B. A, Weiderpass, Elisabete, Amiano, Pilar, Wark, Petra A, Kühn, Tilman, Katzke, Verena, Huerta, José María, Ardanaz, Eva, Quirós, José Ramón, Affret, Aurélie, His, Mathilde, Boutron Ruault, Marie Christine, Peeters, Petra H, Ye, Weimin, Sund, Malin, Boeing, Heiner, Iqbal, Khalid, Ohlsson, Bodil, Sonestedt, Emily, Tjønneland, Anne, Petersen, Kristina En, Travis, Ruth C, Skeie, Guri, Agnoli, Claudia, Panico, Salvatore, Palli, Domenico, Tumino, Rosario, Sacerdote, Carlotta, Freisling, Heinz, Huybrechts, Inge, Overvad, Kim, Trichopoulou, Antonia, Bamia, Christina, Vasilopoulou, Effie, Wareham, Nick, Khaw, Kay Tee, Cross, Amanda J, Ward, Heather A, Riboli, Elio, Duell, Eric J., Wareham, Nicholas [0000-0003-1422-2993], Khaw, Kay-Tee [0000-0002-8802-2903], Apollo - University of Cambridge Repository |
Jazyk: | angličtina |
Rok vydání: | 2017 |
Předmět: |
Male
Oncology Cancer Research Mediterranean diet Epidemiology pancreatic cancer Diet Mediterranean EPIC COHORT 0302 clinical medicine Risk Factors Surveys and Questionnaires PARTICIPANTS Prospective Studies 030212 general & internal medicine Prospective cohort study Pancreas cancer POPULATION 2. Zero hunger education.field_of_study Middle Aged Prognosis 3. Good health European Prospective Investigation into Cancer and Nutrition 030220 oncology & carcinogenesis Female Life Sciences & Biomedicine Cohort study COUNTRIES medicine.medical_specialty Population White People 03 medical and health sciences Mediterranean cooking Breast cancer ADHERENCE SDG 3 - Good Health and Well-being Internal medicine Pancreatic cancer Cuina mediterrània medicine cohort study Journal Article Humans BREAST-CANCER Oncology & Carcinogenesis education Life Style Càncer de pàncrees METAANALYSIS Neoplasm Staging Proportional Hazards Models Cancer prevention Science & Technology business.industry VDP::Medical disciplines: 700::Clinical medical disciplines: 750::Oncology: 762 MORTALITY CONSUMPTION medicine.disease Surgery Pancreatic Neoplasms VDP::Medisinske Fag: 700::Klinisk medisinske fag: 750::Onkologi: 762 Nutrition Assessment PATTERNS business 1112 Oncology And Carcinogenesis Follow-Up Studies |
Zdroj: | Molina-Montes, E, Sanchez, M J, Buckland, G, Bueno-de-Mesquita, H B, Weiderpass, E, Amiano, P, Wark, P A, Kuhn, T, Katzke, V, Huerta, J M, Ardanaz, E, Quiros, J R, Affret, A, His, M, Boutron-Ruault, M C, Peeters, P H, Ye, W, Sund, M, Boeing, H, Iqbal, K, Ohlsson, B, Sonestedt, E, Tjonneland, A, Petersen, K E, Travis, R C, Skeie, G, Agnoli, C, Panico, S, Palli, D, Tumino, R, Sacerdote, C, Freisling, H, Huybrechts, I, Overvad, K, Trichopoulou, A, Bamia, C, Vasilopoulou, E, Wareham, N, Khaw, K T, Cross, A J, Ward, H A, Riboli, E & Duell, E J 2017, ' Mediterranean diet and risk of pancreatic cancer in the European Prospective Investigation into Cancer and Nutrition cohort ', British Journal of Cancer, vol. 116, no. 6, pp. 811-820 . https://doi.org/10.1038/bjc.2017.14 Dipòsit Digital de la UB Universidad de Barcelona Recercat. Dipósit de la Recerca de Catalunya instname British Journal of Cancer Molina-Montes, E, Sánchez, M-J, Buckland, G, Bueno-de-Mesquita, H B, Weiderpass, E, Amiano, P, Wark, P A, Kühn, T, Katzke, V, Huerta, J M, Ardanaz, E, Quiros, J R, Affret, A, His, M, Boutron-Ruault, M-C, Peeters, P H, Ye, W, Sund, M, Boeing, H, Iqbal, K, Ohlsson, B, Sonestedt, E, Tjønneland, A, Petersen, K E, Travis, R C, Skeie, G, Agnoli, C, Panico, S, Palli, D, Tumino, R, Sacerdote, C, Freisling, H, Huybrechts, I, Overvad, K, Trichopoulou, A, Bamia, C, Vasilopoulou, E, Wareham, N, Khaw, K-T, Cross, A J, Ward, H A, Riboli, E & Duell, E J 2017, ' Mediterranean diet and risk of pancreatic cancer in the European Prospective Investigation into Cancer and Nutrition cohort ', B J C, vol. 116, no. 6, pp. 811-820 . https://doi.org/10.1038/bjc.2017.14 British Journal of Cancer, 116, 811. Nature Publishing Group |
ISSN: | 0007-0920 |
Popis: | Source at http://doi.org/10.1038/bjc.2017.14 British Journal of Cancer 2017, 116:811–820 Background: The Mediterranean diet (MD) has been proposed as a means for cancer prevention, but little evidence has been accrued regarding its potential to prevent pancreatic cancer. We investigated the association between the adherence to the MD and pancreatic cancer risk within the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort. Methods: Over half a million participants from 10 European countries were followed up for over 11 years, after which 865 newly diagnosed exocrine pancreatic cancer cases were identified. Adherence to the MD was estimated through an adapted score without the alcohol component (arMED) to discount alcohol-related harmful effects. Cox proportional hazards regression models, stratified by age, sex and centre, and adjusted for energy intake, body mass index, smoking status, alcohol intake and diabetes status at recruitment, were used to estimate hazard ratios (HRs) associated with pancreatic cancer and their corresponding 95% confidence intervals (CIs). Results: Adherence to the arMED score was not associated with risk of pancreatic cancer (HR high vs low adherence¼0.99; 95% CI: 0.77–1.26, and HR per increments of two units in adherence to arMED¼1.00; 95% CI: 0.94–1.06). There was no convincing evidence for heterogeneity by smoking status, body mass index, diabetes or European region. There was also no evidence of significant associations in analyses involving microscopically confirmed cases, plausible reporters of energy intake or other definitions of the MD pattern. Conclusions: A high adherence to the MD is not associated with pancreatic cancer risk in the EPIC study. |
Databáze: | OpenAIRE |
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