Association between postprandial symptoms and gastric emptying after sleeve gastrectomy

Autor: Jan S. Burgerhart, Pim W. J. van Rutte, Peter D. Siersema, Paul C. van de Meeberg, André J. P. M. Smout, M. Edelbroek, Johannes F. Smulders, Dirk N. J. Wyndaele
Přispěvatelé: Amsterdam Gastroenterology Endocrinology Metabolism, Gastroenterology and Hepatology
Rok vydání: 2015
Předmět:
Zdroj: Obesity Surgery, 25, 209-14
Obesity surgery, 25(2), 209-214. Springer New York
Obesity Surgery, 25, 2, pp. 209-14
ISSN: 0960-8923
Popis: Contains fulltext : 151954.pdf (Publisher’s version ) (Closed access) BACKGROUND: Laparoscopic sleeve gastrectomy (LSG) is an effective bariatric procedure. However, postprandial symptoms can compromise its beneficial effect. It is not known if a changed gastric emptying and these symptoms are related. This study aimed to assess the association between postprandial symptoms and the gastric emptying pattern after LSG. METHODS: A gastric emptying study with a solid and liquid meal component was performed in the second year after LSG. Before the test, symptoms were assessed using a standardized questionnaire, and during the test, symptoms were scored on a visual analog scale (VAS). Gastric emptying results were expressed as lag phase, half time of gastric emptying (T(1/2)), and caloric emptying rate/minute. RESULTS: Twenty patients (14 F/6 M; age 45.6 +/- 7.7 years, weight 93.4 +/- 28.2 kg, BMI 31.6 +/- 8.1 kg/m(2)) participated in this study; 13 had a low symptom score (/=18, group II). VAS scores for epigastric pain, nausea, and belching were significantly higher in group II. Lag phase (solid) was 6.4 +/- 4.5 min in group I, 7.3 +/- 6.3 in group II (p = 0.94); T(1/2) (solid) was 40.6 +/- 10.0 min in group I, 34.4 +/- 9.3 in group II (p = 0.27); caloric emptying rate was 3.9 +/- 0.6 kcal/min in group I, 3.9 +/- 1.0 kcal/min in group II (p = 0.32). CONCLUSIONS: Patients with postprandial symptoms after LSG reported more symptoms during the gastric emptying study than patients without symptoms. However, there was no difference between gastric emptying characteristics between both groups, suggesting that abnormal gastric emptying is not a major determinant of postprandial symptoms after LSG.
Databáze: OpenAIRE