Metastatic involvement of skeletal muscle from gastric adenocarcinoma
| Autor: | Radamés Ádamo Zuquello, M Garcia-Buitrago, Luis E. Aguirre, J Salcedo, B Ardalan |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
Oncology
Muscle neoplasm medicine.medical_specialty medicine.diagnostic_test business.industry medicine.medical_treatment Cancer Case Report Disease medicine.disease Microbiology Metastasis Radiation therapy 03 medical and health sciences 0302 clinical medicine Infectious Diseases 030220 oncology & carcinogenesis Internal medicine Biopsy medicine Adenocarcinoma Parasitology business Survival rate 030217 neurology & neurosurgery |
| Zdroj: | Oxford Medical Case Reports |
| ISSN: | 2053-8855 |
| Popis: | Gastric cancer represents the fifth most common cancer diagnosis worldwide and the third leading cause of cancer-related mortality. In the USA, the overall 5-year survival rate is 31%, with distant disease nearing 5%. The most common sites of metastasis are the liver and peritoneum. Skeletal muscle involvement has been rarely reported. Since clinical and imaging findings overlap with primary sarcomas, a confirmatory biopsy is required for diagnosis. Prognosis remains poor with treatment options including palliative chemotherapy, radiotherapy and surgical resection. We report the case of a 57-year-old female presenting with extensive involvement of skeletal muscle 10 years after achieving remission. In addition to illustrating the refractoriness and poor outcomes associated with muscle involvement, this case and comprehensive review of the literature highlights important characteristics of disease biology and tumor genomics that warrant detailed discussion and exposition to a wider audience. |
| Databáze: | OpenAIRE |
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