The incidence of thrombocytopenia in adult patients receiving chemotherapy for solid tumors or hematologic malignancies

Autor:	Gerald A. Soff, Joseph K. Park, Carrie M Nielson, Andrea Marongiu, Jaime Shaw
Rok vydání:	2021
Předmět:	Male medicine.medical_specialty Time Factors Anemia medicine.medical_treatment adverse event Neutropenia chemotherapy‐induced thrombocytopenia chemotherapy Gastroenterology Internal medicine hemic and lymphatic diseases Neoplasms Antineoplastic Combined Chemotherapy Protocols medicine Humans Cumulative incidence Public Health Surveillance Aged Retrospective Studies Aged 80 and over Chemotherapy Cytopenia CIT Leukopenia business.industry Incidence (epidemiology) Incidence toxicity Hematology General Medicine Original Articles Middle Aged medicine.disease Thrombocytopenia United States Regimen Hematologic Neoplasms hematologic malignancy Female Original Article solid tumor Disease Susceptibility medicine.symptom business Biomarkers
Zdroj:	European Journal of Haematology
ISSN:	1600-0609
Popis:	Objectives To estimate the risk of thrombocytopenia in various cancers and chemotherapy regimens. Methods Structured patient‐level data from the Flatiron Health Electronic Health Record database were used to identify adult patients who received chemotherapy for a solid tumor or hematologic malignancy from 2012 to 2017. Three‐month cumulative incidence of thrombocytopenia was assessed based on platelet counts, overall and by grade of thrombocytopenia. Co‐occurrence of anemia, neutropenia, and leukopenia was evaluated. Results Of 15,521 patients with solid tumors, 13% had thrombocytopenia within 3 months (platelet count
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::530b6f163e9ffb81fc12f09b10d554be https://pubmed.ncbi.nlm.nih.gov/33544940 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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