Effects of chronic exposure to a pharmaceutical mixture on the three-spined stickleback (gasterosteus aculeatus) population dynamics in lotic mesocosms

Autor: Olivier Palluel, Edith Chadili, Audrey Catteau, Anne Bado-Nilles, Christelle Robert, Cyril Turies, Sébastien Ronkart, Julie Castiglione, Nathalie Gillard, Jean-Marc Porcher, Sandrine Joachim, Younes Mohamed Ismail Hani, Alain Geffard, Naïs Julian, Odile Dedourge-Geffard, Katherine Nott, Rémy Beaudouin, Viviane David
Přispěvatelé: Institut National de l'Environnement Industriel et des Risques (INERIS), Stress Environnementaux et BIOsurveillance des milieux aquatiques (SEBIO), Université Le Havre Normandie (ULH), Normandie Université (NU)-Normandie Université (NU)-Université de Reims Champagne-Ardenne (URCA)-SFR Condorcet, Université de Reims Champagne-Ardenne (URCA)-Université de Picardie Jules Verne (UPJV)-Centre National de la Recherche Scientifique (CNRS)-Université de Reims Champagne-Ardenne (URCA)-Université de Picardie Jules Verne (UPJV)-Centre National de la Recherche Scientifique (CNRS)-Institut National de l'Environnement Industriel et des Risques (INERIS)
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Diclofenac
Bioenergetics
PHARMACEUTICALS
Three-spined stickleback
Health
Toxicology and Mutagenesis
Population Dynamics
Population
Zoology
Gasterosteus
010501 environmental sciences
Aquatic Science
Biology
01 natural sciences
Mesocosm
Predation
03 medical and health sciences
Naproxen
INDIVIDUAL-BASED MODEL
Belgium
Rivers
Animals
14. Life underwater
education
Population dynamics of fisheries
Acetaminophen
030304 developmental biology
0105 earth and related environmental sciences
0303 health sciences
education.field_of_study
MIXTURE
Stickleback
Models
Theoretical
biology.organism_classification
Smegmamorpha
Carbamazepine
Pharmaceutical Preparations
MESOCOSMS
THREE-SPINED STICKLEBACK
13. Climate action
[SDV.TOX]Life Sciences [q-bio]/Toxicology
Female
[SDV.TOX.ECO]Life Sciences [q-bio]/Toxicology/Ecotoxicology
Water Pollutants
Chemical
Zdroj: Aquatic Toxicology
Aquatic Toxicology, Elsevier, 2020, 224, pp.art. 105499. ⟨10.1016/j.aquatox.2020.105499⟩
ISSN: 0166-445X
DOI: 10.1016/j.aquatox.2020.105499⟩
Popis: Pharmaceutical substances are ubiquitous in the aquatic environment and their concentration levels typically range from ng/L up to several μg/L. Furthermore, as those compounds are designed to be highly biologically active, assessing their impacts on non-target organisms is important. Here, we conducted a mesocosm experiment testing a mixture of five pharmaceuticals (diclofenac, carbamazepine, irbesartan, acetaminophen and naproxen) on fish, three-spined stickleback (Gasterosteus aculeatus). The mixture concentration levels were chosen on the basis of the contamination of the Meuse river in Belgium which had been measured previously during a monitoring campaign undertaken in 2015 and 2016. Three nominal mixture concentration levels were tested: the lowest concentration level mixture was composed by environmentally-relevant concentrations that approximate average realistic values for each pharmaceuticals (Mx1); the two other levels were 10 and 100 times these concentrations. Although no impact on stickleback prey was observed, the mixture significantly impaired the survival of female fish introduced in the mesocosms at the highest treatment level without causing other major differences on fish population structure. Impacts on condition factors of adults and juveniles were also observed at both individual and population levels. Using a modelling approach with an individual-based model coupled to a bioenergetic model (DEB-IBM), we concluded that chronic exposure to environmentally-relevant concentrations of five pharmaceuticals often detected in the rivers did not appear to strongly affect the three-spined stickleback populations. Mechanisms of population regulation may have counteracted the mixture impacts in the mesocosms.
Databáze: OpenAIRE
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