Supplementary Figures 1-6 from An Empirical Approach Leveraging Tumorgrafts to Dissect the Tumor Microenvironment in Renal Cell Carcinoma Identifies Missing Link to Prognostic Inflammatory Factors

Autor: James Brugarolas, Somasekar Seshagiri, Steffen Durinck, Zora Modrusan, Eric Stawiski, Jingxuan He, Wenbin Guo, Xin Luo, Jose Torrealba, Alexander Filatenkov, Mingyi Chen, Zhiqun Xie, Christina Stevens, Oreoluwa Onabolu, Danni Luo, Xinlei Wang, Min S. Kim, Allison Joyce, Tiffani McKenzie, Yi-Feng Gu, Qurratulain Yousuf, Leonard D. Goldstein, He Zhang, Jason J. Luke, Ivan Pedrosa, Ze Zhang, Raquibul Hannan, Bijay S. Jaiswal, Payal Kapur, Rong Lu, Tao Wang
Rok vydání: 2023
Popis: Sup. Fig. 1 Simulation analyses show accurate dissection of bulk tumor RNA-Seq data by DisHet. Sup. Fig. 2 Validating immune/stroma component expression dissected by DisHet. Sup. Fig. 3 Comparison of dissection performance of DeMix and DisHet. Sup. Fig. 4 Principal Component Analysis (PCA) shows the clustering of TCGA pan-RCC patients tumors by the tumor-specific genes and eTME-specific genes, respectively. Sup. Fig. 5 CD4 and CD8 immunohistochemistry staining in the Six2-Cre;VhlF/F;Pbrm1F/F and Six2-Cre;VhlF/F;Bap1F/+. Supl. Fig. 6 Clinical manifestations of eTME-NIS patients.
Databáze: OpenAIRE