| Autor: |
Muhammad Umer Butt, Ahmad Jabri, Hani Hamade, Ahmad Al Abdouh, Mohammed Mhanna, Faris Haddadin, Farhan Nasser, Nour Hammad, Deaa Abu Jazar, Ahmad J. Toumar, Aisha Siraj, Kathir Balakumaran, Michel Ilbawi |
| Rok vydání: |
2022 |
| Předmět: |
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| Zdroj: |
Current problems in cardiology. |
| ISSN: |
1535-6280 |
| Popis: |
To examine echocardiographic parameters correlation with clinical severity indices, Alveolar- arterial gradient (A-a gradient), oxygenation index and clinical outcomes in newborns with persistent pulmonary hypertension of the newborn (PPHN). Retrospective cohort study of 67 subjects,35 weeks' gestation with the diagnosis of PPHN admitted to the University of Kentucky neonatal intensive care unit (NICU) between September 2014 and December 2016. High left ventricular end-systolic eccentricity index (EIs) correlates with the overall clinical severity of PPHN as it is associated with higher A-a gradient and oxygenation index (P = 0.0003 and P0.0001, respectively). Elevated EIs was also predictive for the use of inhaled nitric oxide and extracorporeal membrane oxygenation (P = 0.0004 and P0.0001, respectively). EIs value of1.38 provides cutoff value as an objective marker for the need for extracorporeal membrane oxygenation. EIs can be used to assess clinical severity and outcomes and should be reported routinely. Further studies are warranted to confirm these results. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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