Cell-penetrating peptide-modified quantum dots as a ratiometric nanobiosensor for the simultaneous sensing and imaging of lysosomes and extracellular pH

Autor:	Xinrong Zhang, Meng-Chan Xia, Sichun Zhang, Yan Yang
Rok vydání:	2020
Předmět:	Peptide Biosensing Techniques Cell-Penetrating Peptides Nanoconjugates Sulfides Catalysis Rhodamine chemistry.chemical_compound Quantum Dots Cadmium Compounds Materials Chemistry Extracellular Humans Selenium Compounds Fluorescent Dyes chemistry.chemical_classification Microscopy Confocal Rhodamines Metals and Alloys General Chemistry Hydrogen-Ion Concentration Cell function Surfaces Coatings and Films Electronic Optical and Magnetic Materials Microscopy Fluorescence chemistry Zinc Compounds Quantum dot Ceramics and Composites Cell-penetrating peptide Biophysics Lysosomes Derivative (chemistry) HeLa Cells
Zdroj:	Chemical Communications. 56:145-148
ISSN:	1364-548X 1359-7345
DOI:	10.1039/c9cc07596h
Popis:	The selective measurement of cellular pH at specific regions is significant for the in-depth study of cell functions and pathological processes. Herein, we combined our previously developed rhodamine B-labeled cell-penetrating peptide spirolactam derivative with quantum dots to create a ratiometric nanobiosensor for the simultaneous sensing and imaging of lysosomes and extracellular pH.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52dfc03d58deb679e56575022cdfac03 https://doi.org/10.1039/c9cc07596h Zobrazit plný text záznamu