METODO, A Prospective Observational Study to Assess the Efficacy and Tolerability of Methadone in Heroin-Addicted Patients Undergoing a Methadone Maintenance Treatment: Preliminary Results at Baseline Evaluation
| Autor: | Francisco González-Saiz, Maria Chiara Pieri Pieri, Emanuele Bignamini, Alfio Lucchini, Enrico De Vivo, Metodo Study Team, Pietro Fausto D'Egidio, Claudio Leonardi |
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| Rok vydání: | 2013 |
| Předmět: |
Adult
Male medicine.medical_specialty Methadone maintenance Health (social science) Narcotic Antagonists Medicine (miscellaneous) Heroin Internal medicine Opiate Substitution Treatment medicine Humans Prospective Studies Prospective cohort study Heroin Dependence business.industry Public Health Environmental and Occupational Health Middle Aged Retention rate Psychiatry and Mental health Treatment Outcome Tolerability Anesthesia Female Observational study Opiate business Methadone medicine.drug |
| Zdroj: | Substance Use & Misuse. 48:1530-1540 |
| ISSN: | 1532-2491 1082-6084 |
| DOI: | 10.3109/10826084.2013.800886 |
| Popis: | METODO (methadone efficacy therapy optimization dosage on-going) is a prospective observational study to assess the efficacy and tolerability of methadone in 500 heroin-addicted patients taking a methadone maintenance treatment, enrolled through 2010 to 2011 in five Italian sites, observed over 2 years. The Opiate Dosage Adequacy Scale has been used for the evaluation of the "adequacy" of the methadone dosage and to stratify patients in adequate and not adequate groups. The treatment efficacy has been evaluated in correlation to the dosage adequacy during the visits. Moreover, patients have been evaluated according to the retention rate and duration of retention in treatment and a series of questionnaires. |
| Databáze: | OpenAIRE |
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