Time course of expression of 'early' genes during long-term posttetanic potentiation in rat hippocampal CA1 field
| Autor: | P. D. Lisachev, O. O. Sokolova, Mark B. Shtark, I. V. Pan, Vladimir O. Pustylnyak |
|---|---|
| Rok vydání: | 2010 |
| Předmět: |
medicine.medical_specialty
JUNB Proto-Oncogene Proteins c-jun Long-Term Potentiation Hippocampus Hippocampal formation c-Fos Polymerase Chain Reaction General Biochemistry Genetics and Molecular Biology hemic and lymphatic diseases Internal medicine medicine Animals RNA Messenger Gene Early Growth Response Protein 1 Messenger RNA biology Chemistry c-jun Long-term potentiation General Medicine Molecular biology Rats body regions Endocrinology biology.protein Proto-Oncogene Proteins c-fos hormones hormone substitutes and hormone antagonists |
| Zdroj: | Bulletin of experimental biology and medicine. 148(3) |
| ISSN: | 1573-8221 |
| Popis: | The expression of egr-1, junB, c-jun, and c-fos genes in rat hippocampal CA1 fi eld was studied by the real-time PCR 30, 60, and 120 min after induction of long-term posttetanic potentiation. The content of egr-1, junB, and c-jun mRNA gradually increased and doubled 120 min after tetanization. The increase in c-jun mRNA level lagged behind the increment of egr-1 and junB. The level of c-fos mRNA increased 30 min after tetanization, returned to the initial level by min 60, and again increased 120 min after induction of long-term posttetanic potentiation. |
| Databáze: | OpenAIRE |
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