| Autor: |
Zhongyan Xiong, Zhijun Geng, Shanshan Lian, Shaohan Yin, Guixiao Xu, Yunfei Zhang, Yongming Dai, Jing Zhao, Lidi Ma, Xin Liu, Hairong Zheng, Chao Zou, Chuanmiao Xie |
| Rok vydání: |
2022 |
| Předmět: |
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| Zdroj: |
Abdominal radiology (New York). 47(6) |
| ISSN: |
2366-0058 |
| Popis: |
Restriction spectrum imaging (RSI) is a novel diffusion MRI model that separates water diffusion into several microscopic compartments. The restricted compartment correlating to the tumor cellularity is expected to be a potential indicator of rectal cancer aggressiveness. Our aim was to assess the ability of RSI model for rectal tumor grading.Fifty-eight patients with different rectal cancer grading confirmed by biopsy were involved in this study. DWI acquisitions were performed using single-shot echo-planar imaging (SS-EPI) with multi-b-values at 3 T. We applied a three-compartment RSI model, along with ADC model and diffusion kurtosis imaging (DKI) model, to DWI images of 58 patients. ROC and AUC were used to compare the performance of the three models in differentiating the low grade (G1 + G2) and high grade (G3). Mean ± standard deviation, ANOVA, ROC analysis, and correlation analysis were used in this study.The volume fraction of restricted compartment CThe three-compartment RSI model was able to discriminate the rectal cancer of low and high grades. The results outperform the traditional ADC model and DKI model in rectal cancer grading. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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