Coronary artery calcification scores improve contrast-induced nephropathy risk assessment in chronic kidney disease patients

Autor: Susumu Suzuki, Toyoaki Murohara, Yohei Shibata, Shingo Harata, Mutsuharu Hayashi, Yoshinari Yasuda, Atsuya Shimizu, Naohiro Osugi, Tomoyuki Ota, Yosuke Tatami, Hideki Ishii
Rok vydání: 2016
Předmět:
Male
Cardiac Catheterization
Time Factors
Physiology
medicine.medical_treatment
030232 urology & nephrology
Contrast Media
Coronary Artery Disease
030204 cardiovascular system & hematology
Coronary Angiography
Kidney
Severity of Illness Index
0302 clinical medicine
Japan
Risk Factors
Odds Ratio
Cardiac catheterization
Aged
80 and over
Framingham Risk Score
Incidence
Acute Kidney Injury
Middle Aged
female genital diseases and pregnancy complications
Nephrology
cardiovascular system
Cardiology
population characteristics
Female
Glomerular Filtration Rate
medicine.medical_specialty
Contrast-induced nephropathy
Renal function
Nephropathy
03 medical and health sciences
Physiology (medical)
Internal medicine
medicine
Humans
cardiovascular diseases
Renal Insufficiency
Chronic
Vascular Calcification
Aged
Chi-Square Distribution
business.industry
nutritional and metabolic diseases
Odds ratio
medicine.disease
Confidence interval
Logistic Models
Multivariate Analysis
business
Kidney disease
Zdroj: Clinical and Experimental Nephrology. 21:391-397
ISSN: 1437-7799
1342-1751
Popis: Coronary artery calcification (CAC) is an independent predictor of cardiovascular morbidity and mortality in chronic kidney disease (CKD) patients. The aim of the present study was to evaluate the predictive value of CAC scores for the incidence of contrast-induced nephropathy (CIN) after cardiac catheterization in non-dialyzed CKD patients. The present study evaluated a total of 140 CKD patients who underwent cardiac catheterization. Patients were stratified into two groups based on the optimal cut-off value of the CAC score, which was graded by a non-triggered, routine diagnostic chest computed tomography scan: CAC score ≥8 (high CAC group); and CAC score 10 % in the baseline serum cystatin C level at 24 h after contrast administration. The mean estimated glomerular filtration rate levels were 41.1 mL/min/1.73 m2, and the mean contrast dose administered was 37.5 mL. Patients with high CAC scores exhibited a higher incidence of CIN than patients with low CAC scores (25.5 vs. 3.2 %, p
Databáze: OpenAIRE
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