18-Hydroxy-11-deoxycorticosterone response to insulin in normal man
Autor: | J. Sulon, A. Odoardi, F. Sciarra, M.A. Mercuri, F. Sparano, G. Giaquinto |
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Rok vydání: | 1978 |
Předmět: |
Adult
Male medicine.medical_specialty Insulin induced hypoglycemia medicine.medical_treatment Hypoglycemia Biochemistry chemistry.chemical_compound Endocrinology Adrenal Cortex Hormones Internal medicine Humans Insulin Medicine Desoxycorticosterone business.industry medicine.disease Highly sensitive Normal volunteers chemistry Growth Hormone business 11-Deoxycorticosterone 18-Hydroxydesoxycorticosterone |
Zdroj: | Journal of Steroid Biochemistry. 9:1061-1063 |
ISSN: | 0022-4731 |
DOI: | 10.1016/0022-4731(78)90032-8 |
Popis: | The response of 18-hydroxy-11-deoxycorticosterone (18-OH-DOC) to insulin induced hypoglycemia has been studied in eight normal volunteers. Following insulin, a marked increase was observed in 18-OH-DOC which was more significant and rapid than plasma corticosteroids but disappeared earlier. The good correlation between 18-OHDOC and the plasma corticosteroids pattern during hypoglycemia further demonstrated the ACTH dependence of this compound which appears to be highly sensitive to stress. |
Databáze: | OpenAIRE |
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