18-Hydroxy-11-deoxycorticosterone response to insulin in normal man

Autor: J. Sulon, A. Odoardi, F. Sciarra, M.A. Mercuri, F. Sparano, G. Giaquinto
Rok vydání: 1978
Předmět:
Zdroj: Journal of Steroid Biochemistry. 9:1061-1063
ISSN: 0022-4731
DOI: 10.1016/0022-4731(78)90032-8
Popis: The response of 18-hydroxy-11-deoxycorticosterone (18-OH-DOC) to insulin induced hypoglycemia has been studied in eight normal volunteers. Following insulin, a marked increase was observed in 18-OH-DOC which was more significant and rapid than plasma corticosteroids but disappeared earlier. The good correlation between 18-OHDOC and the plasma corticosteroids pattern during hypoglycemia further demonstrated the ACTH dependence of this compound which appears to be highly sensitive to stress.
Databáze: OpenAIRE